Antirobe

Antirobe (brand of clindamycin hydrochloride) Capsules (for use in dogs only) and Aquadrops Liquid (for use in dogs and cats) are indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:

Dogs:

• Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius).
  
• Deep wounds and abscesses due to Bacteroides fragilis Prevotella melaninogenicus Fusobacterium necrophorum and Clostridium perfringens.
  
• Dental infections due to Staphylococcus aureus Bacteroides fragilis Prevotella melaninogenicus Fusobacterium necrophorum and Clostridium perfringens.
  
• Osteomyelitis due to Staphylococcus aureus Bacteroides fragilis Prevotella melaninogenicus Fusobacterium necrophorum and Clostridium perfringens.

Cats:

• Skin infections (wounds and abscesses) due to Staphylococcus aureus Staphylococcus intermedius and Streptococcus spp.
  
• Deep wounds and infections due to Clostridium perfringens and Bacteroides fragilis.
  
• Dental infections due to Staphylococcus aureus Staphylococcus intermedius Streptococcus spp. Clostridium perfringens and Bacteroides fragilis.

Available in liquid and capsules. 
For dogs and cats.

ANTIROBE Capsules and ANTIROBE AQUADROPS Liquid contain clindamycin hydrochloride which is the hydrated salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chlorosubstitution of the 7(R)-hydroxyl group of a naturally produced antibiotic produced by Streptomyces lincolnensis var. lincolnensis.

ANTIROBE Capsules (For Use in Dogs Only):
25 mg Capsule each yellow and white capsule contains clindamycin hydrochloride equivalent to 25 mg of clindamycin.
75 mg Capsule each green capsule contains clindamycin hydrochloride equivalent to 75 mg of clindamycin.
150 mg Capsule each light blue and green capsule contains clindamycin hydrochloride equivalent to 150 mg of clindamycin.
300 mg Capsule each light blue capsule contains clindamycin hydrochloride equivalent to 300 mg of clindamycin.

ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Each mL of ANTIROBE AQUADROPS contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol 8.64%.

Clindamycin is an inhibitor of protein synthesis in the bacterial cell. The site of binding appears to be in the 5OS sub-unit of the ribosome. Binding occurs to the soluble RNA fraction of certain ribosomes thereby inhibiting the binding of amino acids to those ribosomes. Clindamycin differs from cell wall inhibitors in that it causes irreversible modification of the protein-synthesizing subcellular elements at the ribosomal level.

WARNINGS
Keep out of reach of children. Not for human use.

PRECAUTIONS
During prolonged therapy of one month or greater periodic liver and kidney function tests and blood counts should be performed.
The use of ANTIROBE occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Therefore the administration of ANTIROBE should be avoided in those species sensitive to the gastrointestinal effects of clindamycin (see CONTRAINDICATIONS). Should superinfections occur appropriate measures should be taken as indicated by the clinical situation.
Patients with very severe renal disease and/or very severe hepatic disease accompanied by severe metabolic aberrations should be dosed with caution and serum clindamycin levels monitored during high-dose therapy. Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore ANTIROBE should be used with caution in animals receiving such agents.
Safety in gestating bitches and queens or breeding male dogs and cats has not been established.

CONTRAINDICATIONS
ANTIROBE Capsules and ANTIROBE AQUADROPS Liquid are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.
Because of potential adverse gastrointestinal effects do not administer to rabbits hamsters guinea pigs horses chinchillas or ruminating animals.

ADVERSE REACTIONS
Side effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea. To report adverse reactions or a suspected adverse reaction call 1-800-793-0596.

WHEN WILL THIS ITEM ARRIVE?

Warehouse Time (1 Business Day)
After your order has been verified, we submit your order to the warehouse and it is ready to ship within 1 business day.  

Time in Transit (1-7 Business Days)
Items shipped using our standard service (ground), will arrive 1-7 days after leaving the warehouse.  Expedited shipments will arrive based on the chosen method (3 day, 2 day, overnight)

Item Arrival = Warehouse Time + Shipping Time

EXPEDITED SHIPPING
If you have chosen expedited shipping we will do our best to process the item in the quickest possible manner, and you will receive the item based on the chosen method of service (3 Day, 2 Day, overnight) an overnight order may take more than one business day for the product to arrive.